在第一项研究中，来自美国梅奥诊所的Melissa Murray, Ph.D.及其研究团队发现，与女性相比，男性患者可能更容易被误诊。基于佛罗里达州脑库数据，研究者对1,606名阿尔茨海默病患者的大脑进行分析（年龄范围37-102岁）。
Alzheimer's disease is often misdiagnosed,possibly more so in men, two new studies reveal. The results of both studies were presented at the annual Alzheimer's Association International Conference,held from July 22 to 28 in Toronto.
In the first study, a team of researchers from the Mayo Clinic in Jacksonville, Fla., led by Melissa Murray, Ph.D., foundthat men may be misdiagnosed more often than women. This study included information from the State of Florida brain bank. The researchers examined 1,606 brains of Alzheimer's patients ranging in age from 37 to 102.
One reason for a higher rate of misdiagnosis in men may be that men in the study seemed to develop Alzheimer'sat a younger age than women and had a more aggressive form of the disease. Mentended to develop Alzheimer's in their 60s, while women developed it in their70s, 80s, and 90s, Murray told HealthDay. Men also seemed to have different disease-related brain pathology than women. This may account for the misdiagnosis among men, because their symptoms can be different than those of women, Murray said. She added that men's symptoms may be behavioral, or theremay be language difficulty or motor problems instead of the memory problemsusually associated with Alzheimer's.
In the second study, researchers from the Keenan Research Centre for Biomedical Science at St. Michael's Hospital inToronto looked at inconsistencies between clinical and autopsy diagnoses in 1,073 individuals listed in the National Alzheimer's Coordinating Center database. The team found that 78.4 percent of the patients had a correct diagnosis in the clinic, which was later confirmed in an autopsy of the brain.However, 10.8 percent of those diagnosed with Alzheimer's in the clinic didn'thave the disease. And, another 10.8 percent who weren't diagnosed withAlzheimer's actually had the disease.